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Invitrogen™ JARID1C Polyclonal Antibody
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Catalog No. PIPA583807
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100 μL
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PIPA583807 100 μL
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Catalog No. PIPA583807 Supplier Invitrogen™ Supplier No. PA583807
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LGLMAKDKTL RKKDKEGPEC PPTVVVKEEL GGDVKVESTS PKTFLESKEE LSHSPEPCTK MTMRLRRNHS NAQFIESYVC RMCSRG Highest antigen sequence indentity to the following orthologs: Mouse - 98%, Rat - 91%.

Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.; Isoform 4 can activate the JNK pathway. Involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JARID1C
Applications Immunocytochemistry, Immunofluorescence
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KDM5C
Gene Accession No. P41229
Gene Alias D930009K15Rik; DXS1272E; Histone demethylase JARID1C; JARID1C; JmjC domain-containing protein SMCX; jumonji, AT rich interactive domain 1C (Rbp2 like); Jumonji, AT rich interactive domain 1C (RBP2-like); Jumonji/ARID domain-containing protein 1C; KDM5C; Kiaa0234; lysine (K)-specific demethylase 5C; lysine demethylase 5C; lysine-specific demethylase 5C; mKIAA0234; MRX13; MRXJ; MRXSCJ; MRXSJ; Protein SmcX; Protein Xe169; RGD1560601; sele; selected mouse cDNA on the X; SMCX; Smcx homolog, X chromosome; Smcy homolog, X-linked; XE169
Gene Symbols KDM5C
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human KDM5C. Recombinant protein control fragment (Product #RP-106111).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8242
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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