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Invitrogen™ JHDM1D Polyclonal Antibody
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Catalog No. PIPA589986
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100 μL
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PIPA589986 100 μL
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Catalog No. PIPA589986 Supplier Invitrogen™ Supplier No. PA589986
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Rabbit Polyclonal Antibody

Immunogen sequence: WHRHDYTEVD DGSKPVQAGT RAFVKELRSR VFPSADEIIV KMHGSQLTQR YLEKHGFDVP IMVPKLDDLG LRLPSPAFSV MDVERYVGGD KVIDVIDVAR Q.

JHDM1D histone demethylase that specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JHDM1D
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.34 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KDM7A
Gene Accession No. Q6ZMT4
Gene Alias A630082K20Rik; BB041802; ENSMUSG00000073143; histone lysine demethylase JHDM1D; Jhdm1d; JmjC domain-containing histone demethylation protein 1D; jumonji C domain containing histone demethylase 1; jumonji C domain containing histone demethylase 1 homolog D; jumonji C domain-containing histone demethylase 1 homolog D; Kdm7; Kdm7a; Kiaa1718; lysine (K)-specific demethylase 7A; lysine demethylase 7A; lysine-specific demethylase 7; Lysine-specific demethylase 7A; mKIAA1718
Gene Symbols KDM7A
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80853
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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