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Invitrogen™ JMJD2B Polyclonal Antibody
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Catalog No. PIPA5114131
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100 μL
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PIPA5114131 100 μL
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Catalog No. PIPA5114131 Supplier Invitrogen™ Supplier No. PA5114131
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SASRASLKAK LLRRSHRKRS QPKKPKPEDP KFPGEGTAGA ALLEEAGGSV For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 92%; Dog: 93%; Guinea Pig: 83%; Horse: 93%; Human: 100%; Mouse: 82%; Pig: 93%; Rat: 100%.

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen JMJD2B
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene KDM4B
Gene Accession No. O94953
Gene Alias 4732474L06Rik; JHDM3B; JmjC domain-containing histone demethylation protein 3B; Jmjd2b; jumonji domain containing 2B; jumonji domain-containing protein 2B; KDM4B; KIAA0876; lysine (K)-specific demethylase 4B; lysine demethylase 4B; lysine-specific demethylase 4B; mKIAA0876; TDRD14B; tudor domain containing 14B
Gene Symbols KDM4B
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human JMJD2B.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23030
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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