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Invitrogen™ JMJD2B Polyclonal Antibody
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Catalog No. PIPA5120953
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100 μL
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PIPA5120953 100 μL
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Catalog No. PIPA5120953 Supplier Invitrogen™ Supplier No. PA5120953
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Description

Rabbit Polyclonal Antibody

Positive test controls include: Mouse brain. The target is usually found in the following locations: Nucleus. Immunogen sequence: MGSEDHGAQN PSCKIMTFRP TMEEFKDFNK YVAYIESQGA HRAGLAKIIP PKEWKPRQTY DDIDDVVIPA PIQQVVTGQS GLFTQYNIQK KAMTVGEYRR LANSEKYCTP RHQDFDDLER KYWKNLTFVS PIYGADISGS LYDDDVAQWN IGSLRTILDM VERECGTIIE GVNTPYLYFG MWKTTFAWHT EDMDLYSINY LHFGEPKSWY AIPPEHGKRL ERLAIGFFPG SSQGCDAFLR HKMTLISPII LKKYGIPFSR ITQEAGEFMI TFPYGYHAGF NHGFNCAEST NFATLRWIDY GKVATQCTCR KDMVKISMDV FVRILQPERY ELWKQGKDLT VLDHTRPTAL TSPELSSWSA SRASL.

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen JMJD2B
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.58 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene KDM4B
Gene Accession No. O94953, Q91VY5
Gene Alias 4732474L06Rik; JHDM3B; JmjC domain-containing histone demethylation protein 3B; Jmjd2b; jumonji domain containing 2B; jumonji domain-containing protein 2B; KDM4B; KIAA0876; lysine (K)-specific demethylase 4B; lysine demethylase 4B; lysine-specific demethylase 4B; mKIAA0876; TDRD14B; tudor domain containing 14B
Gene Symbols KDM4B
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-365 of human KDM4B/JMJD2B (NP_0558301).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 193796, 23030
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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