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Invitrogen™ JMJD2B Recombinant Rabbit Monoclonal Antibody (JE36-58)
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Catalog No. FEMA550831
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100 μL
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FEMA550831 100 μL
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Catalog No. FEMA550831 Supplier Invitrogen™ Supplier No. MA550831
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Description

Rabbit Recombinant Monoclonal Antibody

Positive control: HeLa cell lysate, HCT116 cell lysate, SW480 cell lysate, mouse testis tissue lysate, rat testis tissue lysates, human breast carcinoma tissue, HeLa, SW480. Predicted band size: 122 kDa Subcellular Location: Nucleus.

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen JMJD2B
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JE36-58
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene KDM4B
Gene Accession No. O94953, Q91VY5
Gene Alias 4732474L06Rik; JHDM3B; JmjC domain-containing histone demethylation protein 3B; Jmjd2b; jumonji domain containing 2B; jumonji domain-containing protein 2B; KDM4B; KIAA0876; lysine (K)-specific demethylase 4B; lysine demethylase 4B; lysine-specific demethylase 4B; mKIAA0876; TDRD14B; tudor domain containing 14B
Gene Symbols KDM4B
Host Species Rabbit
Immunogen Synthetic peptide within Human JMJD2B aa 97-146.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 193796, 23030
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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