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Invitrogen™ JMJD2C Polyclonal Antibody
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Catalog No. PIPA567044
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100 μL
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PIPA567044 100 μL
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Catalog No. PIPA567044 Supplier Invitrogen™ Supplier No. PA567044
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ARFSTASDMRF EDTFYGADII QGERKRQRVL SSRFKNEYVA DPVYRTFLKS SFQKKCQK Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.

Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3; thereby, playing a central role in histone code. KDM4C does not demethylate histone H3 'Lys-4', H3 'Lys-27', or H4 'Lys-20'. It demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residues. There is no activity on mono- or dimethylated residues. Demethylation of Lys residues generates formaldehyde and succinate.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JMJD2C
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KDM4C
Gene Accession No. Q9H3R0
Gene Alias 2410141F18Rik; AA517467; bA146B14.1; GASC1; GASC-1 protein; gene amplified in squamous cell carcinoma 1; gene amplified in squamous cell carcinoma 1 protein; JHDM3C; JmjC domain-containing histone demethylation protein 3C; JMJD2C; jumonji domain containing 2C; jumonji domain-containing protein 2C; Kdm4c; KIAA0780; lysine (K)-specific demethylase 4C; lysine demethylase 4C; lysine-specific demethylase 4C; RP11-169L18.1; TDRD14C; tudor domain containing 14C
Gene Symbols KDM4C
Host Species Rabbit
Immunogen Recombinant Human JMJD2C. Recombinant protein control fragment (Product #RP-107688).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23081
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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