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Tocris Bioscience™ JMS 17-2 hydrochloride
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Catalog No. 637850
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50 mg
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Catalog No. Quantity
63-785-0 50 mg
63-781-0 10 mg
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Catalog No. 63-785-0 Supplier Tocris Bioscience™ Supplier No. 6378/50
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CX3CR1 antagonist

JMS 17-2 hydrochloride is a chemokine CX3CR1 (fractalkine receptor) antagonist. Inhibits fractalkine-induced ERK phosphorylation and decreases migration of breast cancer cells in vitro. Also inhibits circulating tumor cells from seeding into bone and reduces overall tumor burden in a breast cancer metastasis model.

Specifications

Quantity 50 mg
Molecular Formula C25H26ClN3O.HCl
Formula Weight 456.41
Product Type Antagonist
Purity 98%
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