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Tocris Bioscience™ JNJ 0966
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Catalog No. 643910
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Quantity:
10 mg
50 mg
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Catalog No. 64-391-0

Supplier: Tocris Bioscience™ 6439/10

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Description

Pro-MMP9 activation inhibitor (IC50 = 440 nM)

JNJ 0966 is a pro-MMP9 activation inhibitor (IC50 = 440 nM). Inhibits the conversion of pro-MMP9 to active MMP9, without directly affecting MMP9 enzymatic activity. Exhibits selectivity for pro-MMP9 over pro-MMP1, 2 and 3. Inhibits cell invasion in in vitro assays. Reduces motor impairment in a mouse EAE model. Brain penetrant.

Specifications

Chemical Name or Material N-[2-[(2-Methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]acetamide
CAS 315705-75-0
Quantity 10 mg
Molecular Formula C16H16N4O2S2
Formula Weight 360.45
Purity 98%
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