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  9. JNJ 10191584 maleate, Tocris Bioscience™

JNJ 10191584 maleate, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
869497-75-6
C17H21ClN4O5
396.828
BODOIXYJOORQBQ-UHFFFAOYSA-N
jnj 10191584 maleate
77519402
(6-chloro-1H-benzimidazol-2-yl)-(4-methylpiperazin-1-yl)methanone;formic acid;prop-2-enoic acid
CN1CCN(CC1)C(=O)C2=NC3=C(N2)C=C(C=C3)Cl.C=CC(=O)O.C(=O)O
This item is not returnable. View return policy
869497-75-6
C17H21ClN4O5
396.828
BODOIXYJOORQBQ-UHFFFAOYSA-N
jnj 10191584 maleate
77519402
(6-chloro-1H-benzimidazol-2-yl)-(4-methylpiperazin-1-yl)methanone;formic acid;prop-2-enoic acid
CN1CCN(CC1)C(=O)C2=NC3=C(N2)C=C(C=C3)Cl.C=CC(=O)O.C(=O)O

Description

Selective H4 receptor antagonist; orally active

Highly selective histamine H 4 receptor silent antagonist; binds with high affinity to the human H 4 receptor (K i = 26 nM). > 540-fold selective over the H 3 receptor (K i = 14.1 μM). Inhibits mast cell and eosinophil chemotaxis in vitro with IC 50 values of 138 and 530 nM respectively. Orally active in vivo.
Quantity 10mg
Formula Weight 394.81
Percent Purity >99%
Chemical Name or Material JNJ 10191584 maleate

Safety and Handling

Recommended Storage : Desiccate at Room Temperature