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  7. JNJ 10191584 maleate, Tocris Bioscience™

JNJ 10191584 maleate, Tocris Bioscience™

Catalog Number 244110
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
869497-75-6
C17H21ClN4O5
396.83
MFCD09878266
BODOIXYJOORQBQ-UHFFFAOYSA-N
jnj 10191584 maleate
77519402
6-chloro-2-(4-methylpiperazine-1-carbonyl)-1H-1,3-benzodiazole; formic acid; prop-2-enoic acid
OC=O.OC(=O)C=C.CN1CCN(CC1)C(=O)C1=NC2=CC=C(Cl)C=C2N1
This item is not returnable. View return policy
869497-75-6
C17H21ClN4O5
396.83
MFCD09878266
BODOIXYJOORQBQ-UHFFFAOYSA-N
jnj 10191584 maleate
77519402
6-chloro-2-(4-methylpiperazine-1-carbonyl)-1H-1,3-benzodiazole; formic acid; prop-2-enoic acid
OC=O.OC(=O)C=C.CN1CCN(CC1)C(=O)C1=NC2=CC=C(Cl)C=C2N1

Description

Selective H4 receptor antagonist; orally active

Highly selective histamine H4 receptor silent antagonist; binds with high affinity to the human H4 receptor (Ki = 26 nM). > 540-fold selective over the H3 receptor (Ki = 14.1 μM). Inhibits mast cell and eosinophil chemotaxis in vitro with IC50 values of 138 and 530 nM respectively. Orally active in vivo.
Quantity 10 mg
Formula Weight 394.81
Percent Purity >99%
Chemical Name or Material JNJ 10191584 maleate

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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