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  5. Tocris Bioscience™ JNJ 10191584 maleate

Tocris Bioscience™ JNJ 10191584 maleate
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Catalog No. 244110
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective H4 receptor antagonist; orally active

Highly selective histamine H4 receptor silent antagonist; binds with high affinity to the human H4 receptor (Ki = 26 nM). > 540-fold selective over the H3 receptor (Ki = 14.1 μM). Inhibits mast cell and eosinophil chemotaxis in vitro with IC50 values of 138 and 530 nM respectively. Orally active in vivo.

Chemical Identifiers

CAS 869497-75-6
Molecular Formula C17H21ClN4O5

Specifications

Quantity 10 mg
Formula Weight 394.81
Purity >99%
Molecular Weight (g/mol) 396.83
Chemical Name or Material JNJ 10191584 maleate

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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