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  5. R&D Systems™ JNJ 39758979 Dihydrochloride

R&D Systems™ JNJ 39758979 Dihydrochloride
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Catalog No. 62795 Shop All Novus Products
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62-795 5 mg
62-792-5 25 mg
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Catalog No. 62-795 Supplier R&D Systems™ Supplier No. 6279/5

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Description

A Tocris product, part of R&D Systems. High affinity and selective histamine H4 antagonist; orally bioavailable

JNJ 39758979 dihydrochloride is a high affinity and selective histamine H4 antagonist (Ki = 12.5 nM). Exhibits >80-fold selectivity for H4 over other histamine receptors and no significant activity at a range of other targets. Inhibits histamine-induced eosinophil shape change in whole blood in vitro and ovalbumin-induced inflammation in ovalbumin-sensitized mice in vivo. Orally bioavailable.

Specifications

Chemical Name or Material 4-[(3R)-3-Amino-1-pyrrolidinyl]-6-(1-methylethyl)-2-pyridinamine dihydrochloride
Quantity 5 mg
Product Line Tocris
Molecular Formula C11H19N5.2HCl
Formula Weight 294.22
Purity 98%
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