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Tocris Bioscience™ JNJ 47965567
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Catalog No. 529910
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52-991-0 10 mg
52-995-0 50 mg
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Description

Potent and selective P2X7 antagonist; brain penetrant

JNJ 47965567 is a potent and selective P2X7 antagonist (pIC50 values are 8.3, 7.5 and 7.2 for human, mouse and rat receptors respectively). Selective over a panel of 50 other receptors, ion channels and transporters. Reduces BzATP -induced IL-1β release from monocytes in vitro and from rat brain in vivo. Attenuates amphetamine -induced hyperactivity in rats. Brain penetrant.

Specifications

Purity >98%
Quantity 10 mg
Product Type JNJ 47965567
Molecular Weight (g/mol) 488.64
Inhibitors JNJ 47965567

For Research Use Only

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