Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 804750

Tocris Bioscience™ JP-2-196 alkyne

Catalog No. 804750
Click to view available options
:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

RNF126 chemical handle; alkyne functionalized version of JP-2-196 (Cat. No. 8046).

JP-2-196 alkyne is a covalent RNF126 chemical handle that binds to several other RING E3 ubiquitin ligases including RNF14, RNF40, RNF219, MID2, and LRSAM1. By facilitating E3 ligase recruitment, JP-2-196 alkyne induces proteasomal degradation of diverse target proteins. It serves as a modular scaffold for the design and synthesis of molecular glue degraders. JP-2-196 alkyne is an alkyne functionalized version of JP-2-196 (Cat. No. 8046).

Specifications

Chemical Name or Material 1-(4-Methoxyphenyl)-4-[4-(2-propyn-1-yl)-1-piperazinyl]-2-butene-1,4-dione
CAS 2901113-25-3
Quantity 50 mg
Target Molecular Glues
Molecular Formula C18H20N2O3
Purity 0.95
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.