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Invitrogen™ JRK Polyclonal Antibody
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Catalog No. PIPA5144047
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100 μg
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PIPA5144047 100 μg
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Catalog No. PIPA5144047 Supplier Invitrogen™ Supplier No. PA5144047
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Description

Rabbit Polyclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human A375 whole cell, human A431 whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The JRK gene encodes a protein known as JRK (Jerky) homolog, which is implicated in various cellular processes, including DNA damage response and transcription regulation. JRK is conserved across multiple species and plays a role in the stability of neuronal functions and development. It is notably associated with neuropsychiatric disorders, where aberrations in its expression or function can contribute to conditions such as epilepsy and intellectual disabilities. The protein interacts with other cellular components to influence gene expression patterns, which are critical for maintaining normal neuronal activity. JRK is also studied for its potential involvement in cancer biology, where it may impact cell cycle regulation and genomic stability. Understanding the functions and mechanisms of JRK can provide insights into its roles in both normal physiological processes and disease states, particularly in the context of the nervous system and cancer.
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Specifications

Antigen JRK
Applications Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.01mg sodium azide
Gene JRK
Gene Accession No. O75564
Gene Alias jerky; jerky homolog; jerky protein; Jerky protein homolog; JH8; JRK; Jrk helix-turn-helix protein; Jrk homolog
Gene Symbols JRK
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence of human JRK (LYDIRAHKAQLLRFFA) (aa 52-67).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8629
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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