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Invitrogen™ JSRP1 Monoclonal Antibody (6A9)
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Catalog No. PIMA524513
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100 μg
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Catalog No. Quantity
PIMA524513 100 μg
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Catalog No. PIMA524513 Supplier Invitrogen™ Supplier No. MA524513
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Description

Mouse Monoclonal Antibody

Peptide Sequence: MSMTTRAWEE LDGGLGSCQA LEDHSALAET QEDRASATPR LADSGSVPHD SQVAEGPSVD TRPKKMEKEP AARGTPGTGK ERLKAGASPR SVPARKKAQT.

The junction between the transverse tubules (T-tubules) and the sarcoplasmic reticulum (SR) of skeletal muscle is called the triad. At the triad, dihydropyridine receptors (DHPR) of the T-tubule serve as voltage sensors in excitation-contraction coupling, while ryanodine receptors (RyR), the calcium release channels, exist in the membrane of the terminal cisternae of the SR. It is thought that during slow phase depolarization of the T-tubule, a third protein, triadin (95 kDa) transmits electrochemical signals to the SR through direct interaction with both DHPR and RyR. Another skeletal muscle specific 90 kDa protein has also been localized to the this junction. This protein is phosphorylated by an intrinsic protein kinase in triads suggesting that it may play an important regulatory or structural role in the skeletal muscle triad junction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JSRP1
Applications ELISA, Western Blot
Classification Monoclonal
Clone 6A9
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene JSRP1
Gene Accession No. Q96MG2
Gene Alias 2300003C06Rik; 2310032K21Rik; homolog of mouse skeletal muscle sarcoplasmic reticulum protein JP-45; JP45; JP-45; Jsrp1; Junctional sarcoplasmic reticulum protein 1; Junctional SR; junctional-face membrane protein of 45 kDa homolog; skeletal muscle sarcoplasmic reticulum protein JP-45
Gene Symbols JSRP1
Host Species Mouse
Immunogen JSRP1 (NP_653217.1, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 126306
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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