Invitrogen™ JTB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA576608

Catalog No. PIPA576608

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.

Specifications

• Antigen: JTB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: JTB
• Gene Alias: hJT; HJTB; HSPC222; Jtb; jumping translocation breakpoint; jumping translocation breakpoint protein; PAR; PAR protein; Prostate androgen-regulated protein; protein JTB
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10899, 29439
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O76095, O88823
• Gene Symbols: JTB
• Immunogen: Recombinant fusion protein of human JTB.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG