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Invitrogen™ JTB Polyclonal Antibody
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Catalog No. PIPA587891
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PIPA587891 100 μL
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Catalog No. PIPA587891 Supplier Invitrogen™ Supplier No. PA587891
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Rabbit Polyclonal Antibody

Immunogen sequence: EAPVQEEKLS ASTSNLPCWL VEEFVVAEEC SPCSNFRAKT TPECGPTGYV EKITCSSSKR NEFKSCRSAL MEQRL; Positive Samples: MCF7, NCI-H460, A375, Rat spleen, Rat thymus; Cellular Location: Cytoplasm, Membrane, Mitochondrion, Single-pass type I membrane protein, centrosome, cytoskeleton, microtubule organizing center, spindle.

Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JTB
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.51 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene JTB
Gene Accession No. O76095, O88823
Gene Alias hJT; HJTB; HSPC222; Jtb; jumping translocation breakpoint; jumping translocation breakpoint protein; PAR; PAR protein; Prostate androgen-regulated protein; protein JTB
Gene Symbols JTB
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 31-105 of human JTB (NP_0066851).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10899, 29439
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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