Tocris Bioscience™ K 02288 

Type 1 BMP receptor inhibitor

Manufacturer:  Tocris Bioscience™ 4986/10

Catalog No. 49-861-0R

Description

Potent and selective inhibitor of type I bone morphogenic protein (BMP) receptors (IC50 values are 1.1, 1.8, 6.4, 34.4, 220, 302 and 321 nM for ALK2, ALK1, ALK6, ALK3, ActRIIA, ALK4 and ALK5 respectively). Reduces BMP4-induced Smad1/5/8 phosphorylation in vitro (IC50 = 100 nM) and induces dorsalization of zebrafish embryos.

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Specifications

• Product Type: K 02288
• Purity: >99
• Quantity: 10mg

• Inhibitors: K 02288
• Molecular Weight: 352.38

For Research Use Only