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Invitrogen™ K-cadherin Polyclonal Antibody
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Catalog No. PIPA547373
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100 μg
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Catalog No. Quantity
PIPA547373 100 μg
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Catalog No. PIPA547373 Supplier Invitrogen™ Supplier No. PA547373
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Description

Sheep Polyclonal Antibody

In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) Cadherin-8, rhCadherin-11, and rhCadherin-12 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4), whereas kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. Cadherin-6 is expressed in the proximal tubule epithelium of the kidney from which most renal cell carcinomas are derived.
TRUSTED_SUSTAINABILITY

Specifications

Antigen K-cadherin
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene CDH6
Gene Accession No. P55285
Gene Alias CAD6; CADH6; cadherin 6; cadherin 6, type 2, K-cadherin; cadherin 6, type 2, K-cadherin (fetal kidney); Cadherin6; cadherin-6; Cdh6; k cadherin; KCAD; K-cadherin; Kidney cadherin
Gene Symbols CDH6
Host Species Sheep
Immunogen Mouse myeloma cell line NS0-derived recombinant human Cadherin-6 Thr22-Ala615.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1004
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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