Invitrogen™ K-Ras (Q61R Mutant) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143385

Catalog No. PIPA5143385

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily A single amino acid substitution is responsible for an activating mutation The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Specifications

• Antigen: K-Ras (Q61R Mutant)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: P29466, P48729, Q8N752
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 122011, 1452, 834
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.54 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
• Gene Alias: CFC2; c-Ki-ras2; C-K-RAS; KI-RAS; K-Ras; KRAS proto-oncogene, GTPase; KRAS1; KRAS2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; NS; NS3; RALD; RASK2
• Immunogen: Carrier-protein conjugated synthetic peptide surrounding mutant Q61R of human K-Ras. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG