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Invitrogen™ Kaiso Monoclonal Antibody (6F)
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Catalog No. 358500
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35-850-0 100 μg
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Catalog No. 35-850-0 Supplier Invitrogen™ Supplier No. 358500
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Description

Mouse Monoclonal Antibody

Kaiso Monoclonal Antibody for Western Blot, ICC/IF, IP, ELISA

This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensusKAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-alpha 2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kaiso
Applications ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 6F
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene ZBTB33
Gene Accession No. Q86T24, Q8BN78
Gene Alias AW260253; E130014G12Rik; Kaiso; kaiso transcription factor; RGD1566309; RP23-322E15.9; Transcriptional regulator Kaiso; WUGSC:H_DJ525N14.1; Zbtb33; zinc finger and BTB domain containing 33; zinc finger and BTB domain-containing protein 33; zinc finger transcription factor Kaiso; ZNF348; ZNF-kaiso
Gene Symbols ZBTB33
Host Species Mouse
Immunogen Fusion protein encompassing the N-terminus of mouse Kaiso.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10009, 100348939, 100685062, 422367, 501506, 56805
Target Species Human, Mouse, Rat, Canine, Rabbit, Chicken
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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