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Invitrogen™ KAL1 Monoclonal Antibody (OTI5E10)
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Catalog No. PIMA527048
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100 μL
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PIMA527048 100 μL
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Catalog No. PIMA527048 Supplier Invitrogen™ Supplier No. MA527048
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Description

Mouse Monoclonal Antibody

KAL1 Monoclonal Antibody for IHC (P)

KAL1 (Anosmin-1) an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KAL1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone OTI5E10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ANOS1
Gene Accession No. P23352
Gene Alias Adhesion molecule-like X-linked; ADMLX; ANOS1; anosmin; anosmin 1; Anosmin1; anosmin-1; HH1; HHA; KAL; KAL1; KALIG1; KALIG-1; Kallmann syndrome interval gene 1; kallmann syndrome protein; Kallmann syndrome-1 sequence (anosmin-1); KMS; WAP four-disulfide core domain 19; WFDC19
Gene Symbols ANOS1
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 129-373 of KAL1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3730
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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