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KAL1 Mouse anti-Human, Clone: OTI5E10, liquid, TrueMAB™
Mouse Monoclonal Antibody
Supplier: OriGene TA808743
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DescriptionKAL1 (Anosmin-1) an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.
|ADMLX, HH1, HHA, KAL, KAL1, KALIG-1, KMS, WFDC19|
|-20° C, Avoid Freeze/Thaw Cycles|
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|Human recombit protein fragment corresponding to amino acids 129-373 of human KAL1 produced in E.coli.|
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