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Invitrogen™ KAL1 Polyclonal Antibody
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Catalog No. PIPA575526
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100 μL
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Catalog No. Quantity
PIPA575526 100 μL
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Catalog No. PIPA575526 Supplier Invitrogen™ Supplier No. PA575526
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

KAL1 (Anosmin-1) an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KAL1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene ANOS1
Gene Accession No. P23352
Gene Alias Adhesion molecule-like X-linked; ADMLX; ANOS1; anosmin; anosmin 1; Anosmin1; anosmin-1; HH1; HHA; KAL; KAL1; KALIG1; KALIG-1; Kallmann syndrome interval gene 1; kallmann syndrome protein; Kallmann syndrome-1 sequence (anosmin-1); KMS; WAP four-disulfide core domain 19; WFDC19
Gene Symbols ANOS1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 205-250 of Human Anosmin.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3730
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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