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Invitrogen™ Kallikrein 11 Polyclonal Antibody
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Catalog No. PA14312
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100 μg
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PA14312 100 μg
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Catalog No. PA14312 Supplier Invitrogen™ Supplier No. PA14312
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Description

Rabbit Polyclonal Antibody

PA1-4312 detects the Hippostatin/KLK11 protein in human, mouse, and rat samples. PA1-4312 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~38 kDa protein representing KLK11 in LNCaP cell lysate. PA1-4312 immunizing peptide corresponds to amino acid residues 68-82 of the 35 kDa human hippostasin/KLK11protein. There is 86% sequence identity to mouse and rat.

Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kallikrein 11
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Klk11
Gene Accession No. Q9QYN3, Q9UBX7
Gene Alias 2310015I08Rik; Hippostasin; hK11; kallikrein 11; kallikrein related peptidase 11; kallikrein related-peptidase 11; Kallikrein11; kallikrein-11; Kallikrein-11 inactive chain 1; Kallikrein-11 inactive chain 2; kallikrein-related peptidase 11; KLK11; protease, serine, 20; Prss20; Serine protease 20; TLSP; Trypsin-like protease; UNQ649/PRO1279
Gene Symbols Klk11
Host Species Rabbit
Immunogen Synthetic peptide: Y(68) I V H L G Q H N L Q K E E G(82).
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11012, 292849, 56538
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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