Invitrogen™ Kallikrein 11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528008

Catalog No. PIPA528008

Description

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji , mouse brain. Predicted reactivity: Mouse (81%), Rat (82%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.

Specifications

• Antigen: Kallikrein 11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Klk11
• Gene Alias: 2310015I08Rik; Hippostasin; hK11; kallikrein 11; kallikrein related peptidase 11; kallikrein related-peptidase 11; Kallikrein11; kallikrein-11; Kallikrein-11 inactive chain 1; Kallikrein-11 inactive chain 2; kallikrein-related peptidase 11; KLK11; protease, serine, 20; Prss20; Serine protease 20; TLSP; Trypsin-like protease; UNQ649/PRO1279
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11012, 56538
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9QYN3, Q9UBX7
• Gene Symbols: Klk11
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Kallikrein 11. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG