Invitrogen™ Kallikrein 11 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547164

Catalog No. PIPA547164

Description

In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) Kallikrein 1, rhKallikrein 3, rhKallikrein 5, and rhKallikrein 9 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.

Specifications

• Antigen: Kallikrein 11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Klk11
• Gene Alias: 2310015I08Rik; Hippostasin; hK11; kallikrein 11; kallikrein related peptidase 11; kallikrein related-peptidase 11; Kallikrein11; kallikrein-11; Kallikrein-11 inactive chain 1; Kallikrein-11 inactive chain 2; kallikrein-related peptidase 11; KLK11; protease, serine, 20; Prss20; Serine protease 20; TLSP; Trypsin-like protease; UNQ649/PRO1279
• Host Species: Goat
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11012
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q9UBX7
• Gene Symbols: Klk11
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Kallikrein 11 Ile54-Asn282.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov