Invitrogen™ Kallikrein 6 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547239

Catalog No. PIPA547239

Description

In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) Kallikrein 3, rhKallikrein 5, rhKallikrein 11, rhKallikrein 13, rhKallikrein 14, and rhKallikrein 15 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Kallikreins, including Kallikrein 6, are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.

Specifications

• Antigen: Kallikrein 6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Klk6
• Gene Alias: 0610007D04Rik; AI849898; brain serine protease; BSP; Bssp; Glandular kallikrein K1; hK6; Kal; KAL-B; kallikrein 1; kallikrein 29; kallikrein 6; kallikrein 6 (neurosin); kallikrein 6 (neurosin, zyme); kallikrein 7; kallikrein related peptidase 6; kallikrein related-peptidase 6; kallikrein renal/pancreas/salivary; kallikrein-1; Kallikrein6; Kallikrein-6; Klk1; Klk1b6; Klk29; Klk6; Klk-6; Klk7; MGC9355; mGK-6; MSP; myelencephalon-specific protease; myofibril-bound protease; neurosin; Protease M; protease serine 9 (neurosin); protease, serine, 18; protease, serine, 9; PRSS18; PRSS9; renal kallikrein; Serine protease 18; serine protease 9; SP59; tissue kallikrein-6; true tissue kallikrein; zyme
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5653
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q92876
• Gene Symbols: Klk6
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Kallikrein 6 Glu17-Lys244.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG