Invitrogen™ Kallikrein 6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579569

Catalog No. PIPA579569

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: MCF-7 whole cell, HELA whole cell, MM231 whole cell, MM453 whole cell, A549 whole cell, SMMC whole cell, COLO320 whole cell, SW620 whole cell, HT1080 whole cell. IHC: Human Intestinal Cancer Tissue. ICC/IF: PC-3 Cell.

Kallikreins, including Kallikrein 6, are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.

Specifications

• Antigen: Kallikrein 6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Klk6
• Gene Alias: 0610007D04Rik; AI849898; brain serine protease; BSP; Bssp; Glandular kallikrein K1; hK6; Kal; KAL-B; kallikrein 1; kallikrein 29; kallikrein 6; kallikrein 6 (neurosin); kallikrein 6 (neurosin, zyme); kallikrein 7; kallikrein related peptidase 6; kallikrein related-peptidase 6; kallikrein renal/pancreas/salivary; kallikrein-1; Kallikrein6; Kallikrein-6; Klk1; Klk1b6; Klk29; Klk6; Klk-6; Klk7; MGC9355; mGK-6; MSP; myelencephalon-specific protease; myofibril-bound protease; neurosin; Protease M; protease serine 9 (neurosin); protease, serine, 18; protease, serine, 9; PRSS18; PRSS9; renal kallikrein; Serine protease 18; serine protease 9; SP59; tissue kallikrein-6; true tissue kallikrein; zyme
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5653
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: Q92876
• Gene Symbols: Klk6
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 6 (227-244aa YTNVCRYTNWIQKTIQAK).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG