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Invitrogen™ Kallikrein 8 Monoclonal Antibody (369910)
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Catalog No. PIMA524112
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100 μg
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Catalog No. Quantity
PIMA524112 100 μg
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Catalog No. PIMA524112 Supplier Invitrogen™ Supplier No. MA524112
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Description

Rat Monoclonal Antibody

In direct ELISAs, no cross-reactivity with recombinant human (rh) UPA-1, rhKallikrein 1, 2, 3, 4, 5, 7, 9, 10, 11, 12, 13, 14, 15, rhKallikrein B1, rhHGFA, rhFactor VII, rhFactor X, rhFactor XI, rhProc, or rhThrombin is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kallikrein 8
Applications Immunoprecipitation, Neutralization
Classification Monoclonal
Clone 369910
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene KLK8
Gene Accession No. O60259
Gene Alias brain serine protease 1; BSP1; EGK_10950; H NRPN; hK8; HNP; kallikrein 8; kallikrein 8 (neuropsin/ovasin); kallikrein related peptidase 8; kallikrein related-peptidase 8; Kallikrein8; kallikrein-8; kallikrein-related peptidase 8; Klk8; mK8; neuropsin; NP; Nrpn; Ovasin; PRO322; protease, serine, 19 (neuropsin); Prss19; Serine protease 19; serine protease TADG-14; TADG14; Tumor-associated differentially expressed gene 14 protein; UNQ283; UNQ283/PRO322
Gene Symbols KLK8
Host Species Rat
Immunogen Mouse myeloma cell line NS0-derived recombinant human Kallikrein 8/Neuropsin Gln29-Gly260 (predicted).
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11202
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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