Invitrogen™ Kallikrein 8 Recombinant Rabbit Monoclonal Antibody (038)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA530965

Catalog No. PIMA530965

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human KLK8/Kallikrein 8.

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: Kallikrein 8
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O60259
• Gene Symbols: KLK8
• Immunogen: Recombinant Human KLK8/Kallikrein 8 protein (Met1-Gly260).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA
• Clone: 038
• Conjugate: Unconjugated
• Gene: KLK8
• Gene Alias: brain serine protease 1; BSP1; EGK_10950; H NRPN; hK8; HNP; kallikrein 8; kallikrein 8 (neuropsin/ovasin); kallikrein related peptidase 8; kallikrein related-peptidase 8; Kallikrein8; kallikrein-8; kallikrein-related peptidase 8; Klk8; mK8; neuropsin; NP; Nrpn; Ovasin; PRO322; protease, serine, 19 (neuropsin); Prss19; Serine protease 19; serine protease TADG-14; TADG14; Tumor-associated differentially expressed gene 14 protein; UNQ283; UNQ283/PRO322
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11202
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid