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Invitrogen™ KANK1 Polyclonal Antibody
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Catalog No. PIPA552159
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100 μL
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PIPA552159 100 μL
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Catalog No. PIPA552159 Supplier Invitrogen™ Supplier No. PA552159
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: INVCGVRKRS YSAGNASQLE QLSRARRSGG ELYIDYEEEE METVEQSTQR IKEFRQLTAD MQALEQKIQD SSCEASSELR ENGECRSVAV GAEENMNDIV VYHRGSRSCK DAAVGTLVEM RNCGVSVTEA MLGVMTEADK EIE Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 81%.

Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KANK1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Kank1
Gene Accession No. Q14678
Gene Alias A930031B09Rik; ANKRD15; ankyrin repeat domain 15; ankyrin repeat domain-containing protein 15; AU015049; AW121052; CPSQ2; D330024H06Rik; KANK; Kank1; KIAA0172; Kidney ankyrin repeat-containing protein; KN motif and ankyrin repeat domain-containing protein 1; KN motif and ankyrin repeat domains 1; mKIAA0172
Gene Symbols Kank1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human KANK1. Recombinant protein control fragment (Product #RP-101071).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23189
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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