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Invitrogen™ KAP3 Recombinant Rabbit Monoclonal Antibody (1S7J7)
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Catalog No. PIMA535678
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PIMA535678 100 μL
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Catalog No. PIMA535678 Supplier Invitrogen™ Supplier No. MA535678
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: KFRWHNSQWL EMVESRQMDE SEQYLYGDDR IEPYIHEGDI LERPDLFYNS DGLIASEGAI SPDFFNDYHL QNGDVVGQHS FPGSLGMDGF GQPVGILGRP ATAYGFRPDE PYYYGYGS.

The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KAP3
Applications ELISA, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 1S7J7
Concentration 0.61 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KIFAP3
Gene Accession No. P70188, Q92845
Gene Alias dJ190I16.1; FLA3; KAP-1; KAP3; KAP-3; KIF3AP; Kifap3; kinesin associated protein 3; kinesin-associated protein 3; small G protein GDP dissociation stimulator; SMAP; Smg GDS-associated protein; Smg-GDS
Gene Symbols KIFAP3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 675-792 of human KIFAP3 (Q92845).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16579, 22920, 289168
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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