Invitrogen™ KAP3 Recombinant Rabbit Monoclonal Antibody (1S7J7)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535678

Catalog No. PIMA535678

Description

Immunogen sequence: KFRWHNSQWL EMVESRQMDE SEQYLYGDDR IEPYIHEGDI LERPDLFYNS DGLIASEGAI SPDFFNDYHL QNGDVVGQHS FPGSLGMDGF GQPVGILGRP ATAYGFRPDE PYYYGYGS.

The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: KAP3
• Classification: Recombinant Monoclonal
• Concentration: 0.61 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P70188, Q92845
• Gene Symbols: KIFAP3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 675-792 of human KIFAP3 (Q92845).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 1S7J7
• Conjugate: Unconjugated
• Gene: KIFAP3
• Gene Alias: dJ190I16.1; FLA3; KAP-1; KAP3; KAP-3; KIF3AP; Kifap3; kinesin associated protein 3; kinesin-associated protein 3; small G protein GDP dissociation stimulator; SMAP; Smg GDS-associated protein; Smg-GDS
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16579, 22920, 289168
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid