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Invitrogen™ KAP3 Recombinant Rabbit Monoclonal Antibody (1S7J7)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA535678
Description
Immunogen sequence: KFRWHNSQWL EMVESRQMDE SEQYLYGDDR IEPYIHEGDI LERPDLFYNS DGLIASEGAI SPDFFNDYHL QNGDVVGQHS FPGSLGMDGF GQPVGILGRP ATAYGFRPDE PYYYGYGS.
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.
Specifications
KAP3 | |
Recombinant Monoclonal | |
0.61 mg/mL | |
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P70188, Q92845 | |
KIFAP3 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 675-792 of human KIFAP3 (Q92845). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
ELISA, Western Blot, Immunocytochemistry | |
1S7J7 | |
Unconjugated | |
KIFAP3 | |
dJ190I16.1; FLA3; KAP-1; KAP3; KAP-3; KIF3AP; Kifap3; kinesin associated protein 3; kinesin-associated protein 3; small G protein GDP dissociation stimulator; SMAP; Smg GDS-associated protein; Smg-GDS | |
Rabbit | |
Affinity Chromatography | |
RUO | |
16579, 22920, 289168 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
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