Kappa Light Chain Antibody (SPM508), Alexa Fluor™ 700, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234396AF700

Catalog No. NBP234396Z

Description

Kappa Light Chain Monoclonal specifically detects Kappa Light Chain in Human, Rat (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Kappa Light Chain
• Classification: Monoclonal
• Conjugate: Alexa Fluor 700
• Gene Alias: HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
• Host Species: Mouse
• Molecular Weight of Antigen: 22.5 kDa
• Quantity: 0.1 mL
• Research Discipline: Adaptive Immunity, Immunology
• Gene ID (Entrez): 3514
• Target Species: Human, Rat (Negative)
• Form: Purified

• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: SPM508
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Symbols: IGKC
• Immunogen: Human B-Lymphoma Cells
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1 κ

For Research Use Only