Invitrogen™ Kappa Light Chain Monoclonal Antibody (A11-G11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA544635

Catalog No. PIMA544635

Description

Application notes: Indirect ELISA.

Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Specifications

• Antigen: Kappa Light Chain
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P01601, P01602, P01834, P0DOX7
• Gene Symbols: IGK, IGKC, IGKV1-5, IGKV1D-16
• Immunogen: Native protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ELISA, Western Blot
• Clone: A11-G11
• Conjugate: Unconjugated
• Gene: IGK
• Gene Alias: D4Mit8; HCAK1; ig kappa chain c region; Igk; Igk@; Igkc; Igk-C; IGKCD; IGKV; IGKV15; IGKV1-5; Immunoglobulin K; immunoglobulin kappa chain complex; immunoglobulin kappa constant; immunoglobulin kappa light chain; immunoglobulin kappa locus; immunoglobulin kappa variable 1-5; kappa; Kappa LC; Km; L12; L12a; LOC500183; similar to NGF-binding Ig light chain; V1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 28299, 28901, 3514, 50802
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid