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Invitrogen™ Kappa Light Chain Polyclonal Antibody
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Catalog No. PIPA5115444
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PIPA5115444 100 μL
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Catalog No. PIPA5115444 Supplier Invitrogen™ Supplier No. PA5115444
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Kappa light chain.

Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kappa Light Chain
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene IGK
Gene Accession No. P01601, P01602, P01834, P01837, P0DOX7
Gene Alias D4Mit8; HCAK1; ig kappa chain c region; Igk; Igk@; Igkc; Igk-C; IGKCD; IGKV; IGKV15; IGKV1-5; Immunoglobulin K; immunoglobulin kappa chain complex; immunoglobulin kappa constant; immunoglobulin kappa light chain; immunoglobulin kappa locus; immunoglobulin kappa variable 1-5; kappa; Kappa LC; Km; L12; L12a; LOC500183; similar to NGF-binding Ig light chain; V1
Gene Symbols IGK, IGKC, IGKV1-5, IGKV1D-16
Host Species Rabbit
Immunogen A synthesized peptide derived from human Kappa light chain, corresponding to a region within the internal amino acids.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16071, 243469, 24491, 28299, 28901, 3514, 500183, 50802
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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