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Invitrogen™ KappaB ras1 Polyclonal Antibody
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Catalog No. PIPA566503
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100 μL
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Catalog No. Quantity
PIPA566503 100 μL
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Catalog No. PIPA566503 Supplier Invitrogen™ Supplier No. PA566503
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KEQLHLYDTRG LQEGVELPKH YFSFAD Highest antigen sequence identity to the following orthologs - mouse 96%, rat 100%.

KappaB ras-1 (kappa-B-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with Ikappa-B (Ikappa-B), an inhibitor of the transcription factor NF-kappa-B. Ikappa-B exists in two homologous forms, Ikappa-B-alpha and Ikappa-B-beta, although Ikappa-B-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive Ikappa-B-alpha-NF-kappa-B complexes can shuttle in and out of the nucleus, Ikappa-B-beta-NF-kappa-B complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the Ikappa-B-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of Ikappa-B-beta and regulating the rate of degradation of Ikappa-B-beta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KappaB ras1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NKIRAS1
Gene Accession No. Q9NYS0
Gene Alias 2400004O09Rik; C15orf1; I1PP2A; I-kappa-B-interacting Ras-like protein 1; kappa B-ras 1; kappa B-Ras protein 1; kappaB-Ras1; KBRAS1; LANP; MAPM; MGC119787; MGC150373; NF-kappa-B inhibitor-interacting Ras-like protein 1; NFKB inhibitor interacting Ras like 1; NFKB inhibitor interacting Ras-like 1; NFKB inhibitor interacting Ras-like 1 S homeolog; NFKB inhibitor interacting Ras-like protein 1; Nkiras1; nkiras1.S; PHAP1; PHAPI; PP32; XELAEV_18033117mg
Gene Symbols NKIRAS1
Host Species Rabbit
Immunogen Recombinant Human NKIRAS1. Recombinant protein control fragment (Product #RP-107172).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 28512
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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