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Invitrogen™ KARS Polyclonal Antibody
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Catalog No. PIPA589426
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100 μL
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PIPA589426 100 μL
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Catalog No. PIPA589426 Supplier Invitrogen™ Supplier No. PA589426
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: IAPELYHKML VVGGIDRVYE IGRQFRNEGI DLTHNPEFTT CEFYMAYADY HDLMEITEKM VSGMVKHITG SYKVTYHPDG PEGQAYDVDF TPPFRRINMV EELEKALGMK LPETNLFETE ETRKILDDIC VAKAVECPPP RTTARLLDKL VGEFLEVTCI NPTFICDHPQ IMSPLAKWHR SKEGLTERFE LFVMKKEICN AYTELNDPMR QRQLFEEQAK AKAAGDDEAM FIDENFCTAL EYGLPPTAGW GMGIDRVAMF LTDSNNIKEV LLFPAMKPED KKENVATTDT LESTTVGTSV; Positive Samples: HepG2, Jurkat, HeLa, 293T, Mouse heart, Mouse kidney, Rat liver; Cellular Location: Cell membrane, Cytoplasm, Mitochondrion, Nucleus, Peripheral membrane protein.

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KARS
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 3.14 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene KARS1
Gene Accession No. Q15046, Q5XIM7, Q99MN1
Gene Alias AA589550; AL024334; AL033315; AL033367; CMTRIB; D8Ertd698e; D8Wsu108e; DFNB89; EC 6.1.1.6; KARS; Kars1; KARS2; KIAA0070; KRS; lysine tRNA ligase; lysine--tRNA ligase; LysRS; lysyl-tRNA synthetase; mKIAA0070
Gene Symbols KARS1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 298-597 of human LysRS/LysRS/KARS (NP_0055391).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 292028, 3735, 85305
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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