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KB-RASRabbit anti-Human, Mouse, Rat, Polyclonal, Rockland™

Rabbit Polyclonal Antibody
Supplier: Rockland Immunochemicals 600401273

Description
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. 0
KappaB ras-1 (kappa-B-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with Ikappa-B (Ikappa-B), an inhibitor of the transcription factor NF-kappa-B. Ikappa-B exists in two homologous forms, Ikappa-B-alpha and Ikappa-B-beta, although Ikappa-B-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive Ikappa-B-alpha-NF-kappa-B complexes can shuttle in and out of the nucleus, Ikappa-B-beta-NF-kappa-B complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the Ikappa-B-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of Ikappa-B-beta and regulating the rate of degradation of Ikappa-B-beta.Specifications
KB-RAS | |
Polyclonal | |
Unconjugated | |
NKIRAS1 | |
2400004O09Rik; BOS_23956; C15orf1; I1PP2A; I-kappa-B-interacting Ras-like protein 1; kappa B-ras 1; Kappa B-Ras protein 1; kappaB-Ras1; KBRAS1; LANP; MAPM; MGC119787; MGC150373; NF-kappa-B inhibitor-interacting Ras-like protein 1; NFKB inhibitor interacting Ras like 1; NFKB inhibitor interacting Ras-like 1; NFKB inhibitor interacting Ras-like 1 S homeolog; NFKB inhibitor interacting Ras-like protein 1; Nkiras1; nkiras1.S; PHAP1; PHAPI; PP32; XELAEV_18033117mg | |
Rabbit | |
RUO | |
28512, 305751, 69721 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunoprecipitation, Western Blot | |
1 mg/mL | |
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2 | |
Q8CEC5, Q9NYS0 | |
NKIRAS1 | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody |
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