Invitrogen™ KBTBD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532116

Catalog No. PIPA532116

Description

Recommended positive controls: PC-3. Predicted reactivity: Mouse (89%), Rat (88%), Rhesus Monkey (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The BTB (Broad-Complex, Tram track and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KBTBD3 (kelch repeat and BTB domain-containing protein 3), also known as BKLHD3, is a 608 amino acid protein that contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain and five kelch repeats. The gene encoding KBTBD3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Specifications

• Antigen: KBTBD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KBTBD3
• Gene Alias: 2200003A07Rik; Bklhd3; BTB and kelch domain containing 3; BTB and kelch domain-containing protein 3; Kbtbd3; kelch repeat and BTB (POZ) domain containing 3; kelch repeat and BTB domain containing 3; kelch repeat and BTB domain-containing protein 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 143879
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8NAB2
• Gene Symbols: KBTBD3
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 11 and 268 of Human KBTBD3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov