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Invitrogen™ KCC2 Monoclonal Antibody (N1/12), FITC
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Catalog No. PIMA545496
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Quantity:
100 μg
Catalog No. Quantity
PIMA545496 100 μg
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Catalog No. PIMA545496

Supplier: Invitrogen™ MA545496

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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45496 was sufficient for detection of KCC2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 140kDa. This antibody was formerly sold as clone S1-12.

Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCC2
Applications Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone N1/12
Concentration 1 mg/mL
Conjugate FITC
Formulation PBS, 9.09mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative; pH 7.4
Gene SLC12A5
Gene Accession No. Q63633, Q91V14, Q9H2X9
Gene Alias EIEE34; EIG14; Electroneutral potassium-chloride cotransporter 2; erythroid K-Cl cotransporter 2; furosemide-sensitive K-Cl cotransporter; hKCC2; KCC 2; Kcc2; KCC2a variant 1; KCC2a-S25 variant 1; KCC2b variant 2; K-Cl cotransporter 2; KIAA1176; mKCC2; mKIAA1176; neuronal K-Cl cotransporter; neuronal-specific K-Cl cotransporter; rKCC2; S12A5; SLC12A5; solute carrier family 12 (potassium/chloride transporter), member 5; solute carrier family 12 (potassium-chloride transporter), member 5; solute carrier family 12 member 5; solute carrier family 12, (potassium-chloride transporter) member 5; solute carrier family 12, member 5
Gene Symbols SLC12A5
Host Species Mouse
Immunogen Fusion protein amino acids 932-1043 corresponding to rat KCC2.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171373, 57138, 57468
Target Species Human, Mouse, Rat
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG2a
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