Invitrogen™ KCC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578544

Catalog No. PIPA578544

Description

Positive Control: SK-N-SH, mouse hippocampus, rat hippocampus, rat spinal cord Predicted Reactivity: Mouse (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.

Specifications

• Antigen: KCC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC12A5
• Gene Alias: EIEE34; EIG14; Electroneutral potassium-chloride cotransporter 2; erythroid K-Cl cotransporter 2; furosemide-sensitive K-Cl cotransporter; hKCC2; KCC 2; Kcc2; KCC2a variant 1; KCC2a-S25 variant 1; KCC2b variant 2; K-Cl cotransporter 2; KIAA1176; mKCC2; mKIAA1176; neuronal K-Cl cotransporter; neuronal-specific K-Cl cotransporter; rKCC2; S12A5; SLC12A5; solute carrier family 12 (potassium/chloride transporter), member 5; solute carrier family 12 (potassium-chloride transporter), member 5; solute carrier family 12 member 5; solute carrier family 12, (potassium-chloride transporter) member 5; solute carrier family 12, member 5
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171373, 57138, 57468
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.36 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q63633, Q91V14, Q9H2X9
• Gene Symbols: SLC12A5
• Immunogen: Synthetic peptide encompassing a sequence within the Intracellular domain of mouse KCC2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG