Invitrogen™ KCC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590504

Catalog No. PIPA590504

Description

Immunogen sequence: TKNEREREIQ SITDESRGSI RRKNPANTRL RLNVPEETAG DSEEKPEEEV QLIHDQSAPS CPSSSPSPGE EPEGEGETDP E; Positive Samples: Mouse brain; Cellular Location: Membrane, Multi-pass membrane protein.

Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.

Specifications

• Antigen: KCC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC12A5
• Gene Alias: EIEE34; EIG14; Electroneutral potassium-chloride cotransporter 2; erythroid K-Cl cotransporter 2; furosemide-sensitive K-Cl cotransporter; hKCC2; KCC 2; Kcc2; KCC2a variant 1; KCC2a-S25 variant 1; KCC2b variant 2; K-Cl cotransporter 2; KIAA1176; mKCC2; mKIAA1176; neuronal K-Cl cotransporter; neuronal-specific K-Cl cotransporter; rKCC2; S12A5; SLC12A5; solute carrier family 12 (potassium/chloride transporter), member 5; solute carrier family 12 (potassium-chloride transporter), member 5; solute carrier family 12 member 5; solute carrier family 12, (potassium-chloride transporter) member 5; solute carrier family 12, member 5
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57138
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.15 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q91V14
• Gene Symbols: SLC12A5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 945-1025 of human SLC12A5 (NP_0011282431).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG