Invitrogen™ KCC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550526

Catalog No. PA550526

Description

The antibody detects endogenous levels of total KCC3 / SLC12A6 protein.

SLC12A6 is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.

Specifications

• Antigen: KCC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC12A6
• Gene Alias: 9530023I19Rik; ACCPN; DKFZP434D2135; Electroneutral potassium-chloride cotransporter 3; furosemide-sensitive KCl cotransporter 3; gaxp; Kcc3; KCC3A; KCC3B; K-Cl cotransporter 3; potassium chloride cotransporter 3; potassium chloride cotransporter KCC3a-S3; potassium-chloride transporter-3a; potassium-chloride transporter-3b; SLC12A6; solute carrier family 12 (potassium/chloride transporter), member 6; solute carrier family 12 (potassium/chloride transporters), member 6; solute carrier family 12 member 6; solute carrier family 12, member 6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9990
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q9UHW9
• Gene Symbols: SLC12A6
• Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human Solute carrier family 12 (potassium/chloride transporters), member 6.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG