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Invitrogen™ KCNH1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564954

Catalog No. PIPA564954


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Description

Description

Immunogen sequence: DSCDSGITKSD LRLDNVGEAR SPQDRSPILA EVKHSFYPIP EQTLQATVLE VRHELKEDIK ALNAKMTNIE KQLSEILRIL TSRRSSQSPQ ELFEISRPQS PES Highest antigen sequence identity to the following orthologs - mouse 91%, rat 92%.

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH1 encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. KCNH1 is activated at the onset of myoblast differentiation. KCNH1 is highly expressed in brain and in myoblasts. Overexpression of KCNH1 may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of KCNH1 results in two transcript variants encoding distinct isoforms.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

KCNH1
Polyclonal
Unconjugated
KCNH1
EAG; EAG channel 1; EAG1; ether a go-go; ether-a-go-go potassium channel 1; ether-a-go-go, Drosophila, homolog of; h-eag; hEAG1; Kcnh1; Kv10.1; M-eag; potassium channel, voltage gated eag related subfamily H, member 1; potassium voltage-gated channel subfamily H member 1; potassium voltage-gated channel, subfamily H (eag-related), member 1; r-eag; TMBTS; voltage-gated potassium channel subunit Kv10.1; ZLS1
Rabbit
Antigen Affinity Chromatography
RUO
3756
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry
0.4 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
O95259
KCNH1
Recombinant Human KCNH1. Recombinant protein control fragment (Product #RP-91156).
100 μL
Primary
Human
Antibody
IgG
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