Invitrogen™ KCNJ14 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103645

Catalog No. PIPA5103645

Description

Antibody detects endogenous levels of total KCNJ14.

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium.

Specifications

• Antigen: KCNJ14
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNJ14
• Gene Alias: A930026G01Rik; ATP-sensitive inward rectifier potassium channel 14; Inward rectifier K(+) channel Kir2.4; inwardly rectifying potassium channel KIR2.4; IRK4; IRK-4; KCNJ14; KIR2.4; potassium channel, inwardly rectifying subfamily J member 14; potassium channel, inwardly rectifying subfamily J, member 14; potassium inwardly-rectifying channel J14; potassium inwardly-rectifying channel, subfamily J, member 14; potassium voltage-gated channel subfamily J member 14
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 211480, 276720, 3770
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O70596, Q8JZN3, Q9UNX9
• Gene Symbols: KCNJ14
• Immunogen: A synthesized peptide derived from human KCNJ14(Accession Q9UNX9), corresponding to amino acid residues T386-P436.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov