Invitrogen™ KCNK10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588217

Catalog No. PIPA588217

Description

Immunogen sequence: RLGLDQRAHS LDMLSPEKRS VFAALDTGRF KASSQESINN RPNNLRLKGP EQLNKHGQGA SEDNIINKFG STSRLTKRKN KDLKKTLPED VQKIYKTFRN YSLDEEKKEE ETEKMCNSDN SSTAMLTDCI QQHAELENGM IPTDTKDREP ENNSLLEDRN; Positive Samples: U-87MG, HT-29; Cellular Location: Membrane, Multi-pass membrane protein.

KCNK10 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Three transcript variants have been identified for this gene.

Specifications

• Antigen: KCNK10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNK10
• Gene Alias: 1700024D23Rik; 2P domain potassium channel TREK2; 3010005K24Rik; K2p10.1; Kcnk10; Outward rectifying potassium channel protein TREK-2; outward rectifying potassium channel TREK2; potassium channel subfamily K member 10; potassium channel TREK-2; potassium channel, subfamily K, member 10; potassium channel, two pore domain subfamily K, member 10; potassium two pore domain channel subfamily K member 10; PPP1R97; protein phosphatase 1, regulatory subunit 97; TREK2; TREK-2; TREK-2 K(+) channel subunit; TREK-2 two-pore-domain K+ channel; TWIK-related K+ channel 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54207
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.37 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P57789
• Gene Symbols: KCNK10
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 384-543 of human KCNK10 (NP_6121911).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG