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Invitrogen™ KCNK18 Polyclonal Antibody
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Catalog No. PIPA5114308
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100 μL
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PIPA5114308 100 μL
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Catalog No. PIPA5114308 Supplier Invitrogen™ Supplier No. PA5114308
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Description

Rabbit Polyclonal Antibody

KCNK18 Polyclonal Antibody for Flow, ICC/IF, IHC (P), Western Blot

TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCNK18
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene KCNK18
Gene Accession No. Q6Q1P3, Q6VV64, Q7Z418
Gene Alias 2P K ion channel TRESK; Gm781; K2p18.1; Kcnk18; MGR13; Potassium channel subfamily K member 18; potassium channel, subfamily K, member 18; potassium channel, two pore domain subfamily K, member 18; potassium two pore domain channel subfamily K member 18; tandem-pore K+ (K(2P)) channel; Tresk; TRESK2; Tresk-2; TRIK; TWIK-related individual K+ channel; TWIK-related individual potassium channel; TWIK-related spinal cord K+ channel; TWIK-related spinal cord potassium channel; Two-pore-domain potassium channel TRESK
Gene Symbols KCNK18
Host Species Rabbit
Immunogen Synthetic peptide within mouse KCNK18 aa 44-93.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 332396, 338567, 445371
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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