Invitrogen™ KCNMB3 Monoclonal Antibody (3E5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA521690

Catalog No. PIMA521690

Description

Peptide Sequence: FMLSIQREES TCTAIHTDIM DDWLDCAFTC GVHCHGQGKY PCLQVFVNLS HPGQKALLHY NEEAVQINPK CFYTPKCHQD RNDLLNSALD IKEFFDHKNG.

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.

Specifications

• Antigen: KCNMB3
• Classification: Monoclonal
• Concentration: 0.2-1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9NPA1
• Gene Symbols: KCNMB3
• Immunogen: KCNMB3 (NP_741979, 82 a.a. ~ 181 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Western Blot
• Clone: 3E5
• Conjugate: Unconjugated
• Gene: KCNMB3
• Gene Alias: big potassium channel beta subunit 3; BK beta 3; BK channel beta subunit 3; BK channel subunit beta-3; BKbeta3; calcium-activated potassium channel regulatory subunit; calcium-activated potassium channel subfamily M subunit beta-3; Calcium-activated potassium channel subunit beta-3; calcium-activated potassium channel, subfamily M subunit beta-3; Charybdotoxin receptor subunit beta-3; EG435726; EMBL:BAF79924.1}; Gm5707; HBETA3; K(VCA)BETA-3; KCNMB2; KCNMB3; kcnmb3 {ECO:0000312; KCNMBL; large conductance, voltage and Ca2+ activated potassium channel Maxi K beta 3 subunit; maxi K channel subunit beta-3; MaxiK channel beta-subunit 3; potassium calcium-activated channel subfamily M regulatory beta subunit 3; potassium channel subfamily M regulatory beta subunit 3; potassium large conductance calcium-activated channel, subfamily M beta member 3; potassium large conductance calcium-activated channel, subfamily M, beta member 3; potassium large conductance calcium-activated channel, subfamily M, beta member 4; SLOBETA3; SLO-BETA-3; slobeta3 (KCNMB3)
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27094
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid