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Invitrogen™ KCNMB3 Polyclonal Antibody
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Catalog No. PIPA532891
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50 μg
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PIPA532891 50 μg
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Catalog No. PIPA532891 Supplier Invitrogen™ Supplier No. PA532891
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (94%); Bovine, Bat, Horse (88%); Gibbon, Dog, Pig (82%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCNMB3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene KCNMB3
Gene Accession No. Q9NPA1
Gene Alias big potassium channel beta subunit 3; BK beta 3; BK channel beta subunit 3; BK channel subunit beta-3; BKbeta3; calcium-activated potassium channel regulatory subunit; calcium-activated potassium channel subfamily M subunit beta-3; Calcium-activated potassium channel subunit beta-3; calcium-activated potassium channel, subfamily M subunit beta-3; Charybdotoxin receptor subunit beta-3; EG435726; EMBL:BAF79924.1}; Gm5707; HBETA3; K(VCA)BETA-3; KCNMB2; KCNMB3; kcnmb3 {ECO:0000312; KCNMBL; large conductance, voltage and Ca2+ activated potassium channel Maxi K beta 3 subunit; maxi K channel subunit beta-3; MaxiK channel beta-subunit 3; potassium calcium-activated channel subfamily M regulatory beta subunit 3; potassium channel subfamily M regulatory beta subunit 3; potassium large conductance calcium-activated channel, subfamily M beta member 3; potassium large conductance calcium-activated channel, subfamily M, beta member 3; potassium large conductance calcium-activated channel, subfamily M, beta member 4; SLOBETA3; SLO-BETA-3; slobeta3 (KCNMB3)
Gene Symbols KCNMB3
Host Species Rabbit
Immunogen Synthetic 17 amino acid peptide from internal region of human KCNMB3.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27094
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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